High Blood Pressure and Kidney Disease

Your kidneys play a role in keeping your blood pressure at the right level. This is important because blood pressure is closely related to the health of the kidneys. High blood pressure, also called hypertension, can damage the kidneys.

As blood flows through your veins, it presses against the walls of your blood vessels. Extra fluid in your body increases the volume of fluid in your blood and makes your blood pressure higher. Narrow or clogged blood vessels also raise blood pressure.

High blood pressure makes the heart work harder and, over time, can damage blood vessels throughout the body. If the blood vessels in the kidneys are damaged, they may stop doing their job of removing wastes and extra fluid from the blood. The extra fluid may then raise blood pressure even more.

After diabetes, high blood pressure is the leading cause of kidney failure, commonly called end-stage renal disease (ESRD). Patients with ESRD must either go on dialysis or receive a new kidney through transplant. Every year, high blood pressure causes more than 15,000 new cases of ESRD in the United States.

Most people with high blood pressure do not have any symptoms. The only way to know if your blood pressure is high is to have it measured by a health professional. The measurement consists of two numbers that represent the pressure when your heart is beating and when it is resting between beats. A person's blood pressure is considered high if it goes over 140/90.

African Americans are more likely than whites to have high blood pressure and to develop kidney problems from it even when blood pressure is only mildly elevated. In fact, African Americans ages 25 to 44 are 20 times more likely than their white counterparts to develop hypertension-related kidney failure. The National Institute of Diabetes and Digestive and Kidney Diseases, part of the National Institutes of Health (NIH), is sponsoring a study to find effective ways to prevent hypertension-related ESRD in African Americans.

The National Heart, Lung, and Blood Institute, also part of NIH, has found that four steps can help control blood pressure:

• Control your weight.
• Limit your sodium intake.
• Get plenty of exercise.
• Avoid excessive consumption of alcohol.

Many people need medication to control high blood pressure. A group of medications called ACE inhibitors lower blood pressure and have an added protective effect on the kidney in diabetic patients. If you have high blood pressure, see your doctor regularly.

More information is available from

American Kidney Fund
6110 Executive Boulevard
Rockville, MD 20852
Phone: 1–800–638–8299

National Heart, Lung, and Blood Institute
Information Center
P.O.Box 30105
Bethesda, MD 20824–0105
Email: NHLBIinfo@rover.nhlbi.nih.gov
Phone: 301–592–8573

National Kidney Foundation
30 East 33rd Street
New York, NY 10016
Phone: 1–800–622–9010

Additional Information on High Blood Pressure and Kidney Disease

The National Kidney and Urologic Diseases Information Clearinghouse collects resource information on kidney and urologic diseases for the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Reference Collection. This database provides titles, abstracts, and availability information for health information and health education resources. The NIDDK Reference Collection is a service of the National Institutes of Health.

To provide you with the most up-to-date resources, information specialists at the clearinghouse created an automatic search of the NIDDK Reference Collection. To obtain this information, you may view the results of the automatic search on High Blood Pressure and Kidney Disease.

If you wish to perform your own search of the database, you may access and search the NIDDK Reference Collection database online.

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National Kidney and Urologic Diseases Information Clearinghouse

3 Information Way
Bethesda, MD 20892–3580
Phone: 1–800–891–5390
TTY: 1–866–569–1162
Fax: 703–738–4929
Email: nkudic@info.niddk.nih.gov
Internet: www.kidney.niddk.nih.gov

The National Kidney and Urologic Diseases Information Clearinghouse (NKUDIC) is a service of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). The NIDDK is part of the National Institutes of Health of the U.S. Department of Health and Human Services. Established in 1987, the Clearinghouse provides information about diseases of the kidneys and urologic system to people with kidney and urologic disorders and to their families, health care professionals, and the public. The NKUDIC answers inquiries, develops and distributes publications, and works closely with professional and patient organizations and Government agencies to coordinate resources about kidney and urologic diseases.

Publications produced by the Clearinghouse are carefully reviewed by both NIDDK scientists and outside experts.

This publication is not copyrighted. The Clearinghouse encourages users of this publication to duplicate and distribute as many copies as desired.

NIH Publication No. 99–4572
June 1999